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The Cardassian Union and the Federation sign an affiliation treaty allowing free passage through each of their territories. This treaty is frowned upon by the Klingon Empire.
A coup occurs on Romulus when the government is overthrown by a Reman named Shinzon. The USS Enterprise is dispatched to meet with the new Praetor, its crew discovers that Shinzon is weaving an elaborate trap. Shinzon is subsequently killed and the Reman leadership is again replaced by Romulans.
A Starfleet task force led by the USS Titan is dispatched to the Neutral Zone for talks with the new Romulan leadership. After several months of promise these talks break down and communications between the two powers decay.